EUROPAC – The European Registry of Hereditary Pancreatic Diseases
Healthcare professionals can now refer people with a family history of pancreatic cancer to the European Registry of Hereditary Pancreatic Diseases (EUROPAC) for annual surveillance.
Around 10% of pancreatic cancers are caused by inherited risk factors. These can occur in families with a history of either pancreatic cancer or hereditary pancreatitis or in people who carry an at-risk genetic mutation.
NICE guidance (NG85) recommends pancreatic cancer surveillance for people with inherited high risk factors.
EUROPAC is a registry for families with histories of familial pancreatic cancer and hereditary pancreatitis. The EUROPAC study also runs surveillance programmes for people with high-risk factors.
The nearest surveillance centre for patients in the Peninsula Cancer Alliance is University Hospitals Plymouth NHS Trust.
On this page you will find:
- information for healthcare professionals about EUROPAC including potential referral routes into the study for eligible patients
- the patient referral form
- an introduction to Beata Gubacsi, the EUROPAC surveillance navigator for the SSCA region
- A guide to who should be referred onto EUROPAC
Patients who have:
- Two or more First Degree Relatives with pancreatic cancer e.g. parent and grandparent, parent and sibling, parent and aunt/uncle etc.
- Three or more cases of pancreatic cancer in the family
- One or more cases of pancreatic cancer with an associated syndrome
- Peutz-Jeghers syndrome
- Two or more relatives with idiopathic pancreatitis
- One case of idiopathic pancreatitis
- Family history of pancreatitis and PRSS1
For a full list of referral criteria including genetic mutations and diagnosed genetic conditions, refer to the EUROPAC health professional information leaflet.