EUROPAC – The European Registry of Hereditary Pancreatic Diseases

HealthcEUROPACLOGO.jpgare professionals can now refer people with a family history of pancreatic cancer to the European Registry of Hereditary Pancreatic Diseases (EUROPAC) for annual surveillance.

Around 10% of pancreatic cancers are caused by inherited risk factors. These can occur in families with a history of either pancreatic cancer or hereditary pancreatitis or in people who carry an at-risk genetic mutation.

NICE guidance (NG85) recommends pancreatic cancer surveillance for people with inherited high risk factors.

EUROPAC is a registry for families with histories of familial pancreatic cancer and hereditary pancreatitis. The EUROPAC study also runs surveillance programmes for people with high-risk factors.

The nearest surveillance centre for patients in the Peninsula Cancer Alliance is University Hospitals Plymouth NHS Trust.

On this page you will find:

  • information for healthcare professionals about EUROPAC including potential referral routes into the study for eligible patients
  • the patient referral form
  • an introduction to Beata Gubacsi, the EUROPAC surveillance navigator for the SSCA region
  • A guide to who should be referred onto EUROPAC
Who should be referred to EUROPAC?

Patients who have:

  • Two or more First Degree Relatives with pancreatic cancer e.g. parent and grandparent, parent and sibling, parent and aunt/uncle etc.
  • Three or more cases of pancreatic cancer in the family
  • One or more cases of pancreatic cancer with an associated syndrome
  • Peutz-Jeghers syndrome
  • Two or more relatives with idiopathic pancreatitis
  • One case of idiopathic pancreatitis
  • Family history of pancreatitis and PRSS1

For a full list of referral criteria including genetic mutations and diagnosed genetic conditions, refer to the EUROPAC health professional information leaflet.

Self-referral to EUROPAC
Meet our region's EUROPAC surveillance navigator