Systemic Anti Cancer Therapy Protocols

These clinical protocols have been developed by local clinicians, with the support of the South West Clinical Network (SWCN). The information is provided as guidance only, and has no legal or official standing. The guidance does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of each patient, in consultation with the patient and/or their guardian or carer. Availability of treatments may change, subject to NHS funding agreements. These protocols must be used in conjunction with local and national commissioning guidance.

The protocols are still being updated and more will be added to this website as they are completed. If you have any queries or suggestions, or would like to be involved in the development of these protocols please contact us

(R) COCKLE

Salvage

Haematology

(R) GDP – Gemcitabine, Dexamethasone and Cisplatin +/- Rituximab

Salvage

Haematology

(R) DHAP – Cisplatin, Cytarabine and Dexamethasone +/- Rituximab

Salvage

Haematology

Venetoclax

CLL/SLL (specific treatments)

Haematology

Rituximab-Venetoclax

CLL/SLL (specific treatments)

Haematology

Idelalisib and Rituximab

CLL/SLL (specific treatments)

Haematology

(R) Bendamustine (First line for CLL)

CLL/SLL (specific treatments)

Haematology

(R) Bendamustine (Subsequent line for CLL)

CLL/SLL (specific treatments)

Haematology

Ofatumumab

CLL/SLL (specific treatments)

Haematology

Obinutuzumab and Chlorambucil

CLL/SLL (specific treatments)

Haematology

Ibrutinib

CLL/SLL (specific treatments)

Haematology

Fludarabine, Cyclophosphamide and Rituximab (FCR)

CLL/SLL (specific treatments)

Haematology

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